Mal-L-PA-NH-Boc

• CAT Number: I046050
• CAS Number: 1491152-23-8
• Molecular Formula: C12H16N2O6
• Molecular Weight: 284.27
• Purity: ≥95%
• Synonyms: (2S)-2-(2,5-dioxopyrrol-1-yl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
• InChI: InChI=1S/C12H16N2O6/c1-12(2,3)20-11(19)13-6-7(10(17)18)14-8(15)4-5-9(14)16/h4-5,7H,6H2,1-3H3,(H,13,19)(H,17,18)/t7-/m0/s1
• InChIKey: QNSOCOXQLKMHCV-ZETCQYMHSA-N
• SMILES: CC(C)(C)OC(=O)NCC(C(=O)O)N1C(=O)C=CC1=O

Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Reference

[1]. Robert Lyon, et al. Self-stabilizing linker conjugates. WO2013173337A2.