For research use only. Not for therapeutic Use.
Mal-PEG2-acid（Cat No.:I016998） is a non-cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). It can be chemically conjugated with Tubulysin and its cytotoxic derivatives for targeted drug delivery. Additionally, Mal-PEG2-acid can function as a PROTAC linker for PROTAC synthesis. Its versatile nature allows for the development of ADCs and PROTACs, expanding the possibilities for targeted therapy in the field of drug development.
| Catalog Number | I016998 |
| CAS Number | 1374666-32-6 |
| Molecular Formula | C₁₁H₁₅NO₆ |
| Purity | ≥95% |
| Target | PROTAC |
| IUPAC Name | 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid |
| InChI | InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16) |
| InChIKey | TXMDOUPVKVGPIS-UHFFFAOYSA-N |
| SMILES | C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O |
| Reference | [1]. Zhao, Yongxin, et al. Cytotoxin molecule, conjugate and preparation method and application thereof. Faming Zhuanli Shenqing (2019), CN 109912683 A 20190621. |
