For research use only. Not for therapeutic Use.
Mal-PEG2-NHS（Cat No.:I044628）is a heterobifunctional PEG linker with a maleimide group and an N-hydroxysuccinimide (NHS) ester, connected by a short PEG2 spacer. The maleimide selectively reacts with thiol groups on cysteine residues, while the NHS ester efficiently couples with primary amines on proteins, peptides, or other biomolecules. The PEG2 segment enhances solubility and provides flexibility, minimizing steric hindrance in conjugation reactions. Mal-PEG2-NHS is commonly used in bioconjugation, antibody-drug conjugates, and targeted delivery systems, allowing stable and site-specific crosslinking for biomedical and pharmaceutical research applications.
| CAS Number | 329364-72-9 |
| Synonyms | (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]acetate |
| Molecular Formula | C14H16N2O8 |
| Purity | ≥95% |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]acetate |
| InChI | InChI=1S/C14H16N2O8/c17-10-1-2-11(18)15(10)5-6-22-7-8-23-9-14(21)24-16-12(19)3-4-13(16)20/h1-2H,3-9H2 |
| InChIKey | HLLLISBRYDGYSK-UHFFFAOYSA-N |
| SMILES | C1CC(=O)N(C1=O)OC(=O)COCCOCCN2C(=O)C=CC2=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
