Mal-PEG2-oxyamine TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I040224
  • Molecular Formula: C12H17F3N2O7
  • Molecular Weight: 358.27
  • Purity: ≥95%
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Mal-PEG2-oxyamine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


Catalog Number I040224
Synonyms

1-[2-[2-(2-aminooxyethoxy)ethoxy]ethyl]pyrrole-2,5-dione;2,2,2-trifluoroacetic acid

Molecular Formula C12H17F3N2O7
Purity ≥95%
InChI InChI=1S/C10H16N2O5.C2HF3O2/c11-17-8-7-16-6-5-15-4-3-12-9(13)1-2-10(12)14;3-2(4,5)1(6)7/h1-2H,3-8,11H2;(H,6,7)
InChIKey NCWSUMIVBVTGLK-UHFFFAOYSA-N
SMILES C1=CC(=O)N(C1=O)CCOCCOCCON.C(=O)(C(F)(F)F)O

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