For research use only. Not for therapeutic Use.
Mal-PEG2-oxyamine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Catalog Number | I040224 |
Synonyms | 1-[2-[2-(2-aminooxyethoxy)ethoxy]ethyl]pyrrole-2,5-dione;2,2,2-trifluoroacetic acid |
Molecular Formula | C12H17F3N2O7 |
Purity | ≥95% |
InChI | InChI=1S/C10H16N2O5.C2HF3O2/c11-17-8-7-16-6-5-15-4-3-12-9(13)1-2-10(12)14;3-2(4,5)1(6)7/h1-2H,3-8,11H2;(H,6,7) |
InChIKey | NCWSUMIVBVTGLK-UHFFFAOYSA-N |
SMILES | C1=CC(=O)N(C1=O)CCOCCOCCON.C(=O)(C(F)(F)F)O |