Mal-PEG3-NH2 TFA

• CAT Number: I040737
• CAS Number: 2830214-77-0
• Molecular Formula: C14H21F3N2O7
• Molecular Weight: 386.32
• Purity: ≥95%
• Synonyms: 1-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]pyrrole-2,5-dione;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C12H20N2O5.C2HF3O2/c13-3-5-17-7-9-19-10-8-18-6-4-14-11(15)1-2-12(14)16;3-2(4,5)1(6)7/h1-2H,3-10,13H2;(H,6,7)
• InChIKey: XJFZSMGECVGGCF-UHFFFAOYSA-N
• SMILES: C1=CC(=O)N(C1=O)CCOCCOCCOCCN.C(=O)(C(F)(F)F)O

Mal-PEG3-NH2 TFA(CAT: I040737) is a heterobifunctional polyethylene glycol (PEG) linker featuring a maleimide group on one end and a primary amine on the other, provided as the trifluoroacetic acid (TFA) salt. The PEG3 spacer (three ethylene glycol units) enhances solubility and flexibility, minimizing steric hindrance in bioconjugation applications. The maleimide moiety selectively reacts with thiol groups, while the amine enables coupling with carboxyl or activated esters. This reagent is ideal for constructing antibody-drug conjugates, protein labeling, PEGylation, and linker design in drug delivery systems. Mal-PEG3-NH2 TFA supports precise and efficient crosslinking in chemical biology and pharmaceutical research.