For research use only. Not for therapeutic Use.
Maleimide-NOTA is a chelator for the labeling of peptides and antibodies. Maleimide-NOTA can react with cysteine[1].
Catalog Number | I040843 |
CAS Number | 1295584-83-6 |
Synonyms | 2-[4-(carboxymethyl)-7-[2-[2-(2,5-dioxopyrrol-1-yl)ethylamino]-2-oxoethyl]-1,4,7-triazonan-1-yl]acetic acid |
Molecular Formula | C18H27N5O7 |
Purity | ≥95% |
InChI | InChI=1S/C18H27N5O7/c24-14(19-3-4-23-15(25)1-2-16(23)26)11-20-5-7-21(12-17(27)28)9-10-22(8-6-20)13-18(29)30/h1-2H,3-13H2,(H,19,24)(H,27,28)(H,29,30) |
InChIKey | JZFBXLDURQNNQU-UHFFFAOYSA-N |
SMILES | C1CN(CCN(CCN1CC(=O)NCCN2C(=O)C=CC2=O)CC(=O)O)CC(=O)O |
Reference | [1]. Dora Mugoli Chigoho, et al. Site-Specific Radiolabeling of a Human PD-L1 Nanobody via Maleimide-Cysteine Chemistry. Pharmaceuticals (Basel). 2021 Jun 8;14(6):550. |