Mangiferin

• CAT Number: I003665
• CAS Number: 4773-96-0
• Molecular Formula: C19H18O11
• Molecular Weight: 422.34
• Purity: ≥95%
• Target: Apoptosis
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 1,3,6,7-tetrahydroxy-2-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]xanthen-9-one
• InChI: 1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1
• InChIKey: AEDDIBAIWPIIBD-ZJKJAXBQSA-N
• SMILES: C1=C2C(=CC(=C1O)O)OC3=C(C2=O)C(=C(C(=C3)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O

Mangiferin (Cat No.: I003665) is a naturally occurring polyphenolic xanthone found in various parts of the mango tree, particularly leaves and bark. It exhibits potent antioxidant, anti-inflammatory, and antimicrobial properties, contributing to numerous potential health benefits. Research suggests mangiferin may protect against oxidative stress, support immune function, and help manage metabolic disorders. Additionally, it shows promise in regulating blood sugar levels and combating certain pathogens. As a versatile bioactive compound, mangiferin has garnered attention for its potential in future nutraceutical and pharmaceutical applications.

Reference

[1]. Miura T, et al. Antidiabetic activity of a xanthone compound, mangiferin. Phytomedicine. 2001 Mar;8 (2):85-7.

[2]. S Muruganandan, et al. Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicology
Volume 176, Issue 3, 15 July 2002, Pages 165–173

[3]. Leiro JM, et al. In vitro effects of mangiferin on superoxide concentrations and expression of the inducible nitric oxide synthase, tumour necrosis factor-alpha and transforming growth factor-beta genes. Biochem Pharmacol. 2003 Apr 15;65(8):1361-71.