For research use only. Not for therapeutic Use.
MAO-B-IN-17 is a selective monoamine oxidase B (MAO-B) inhibitor with the IC50 value of 5.08 μM. MAO-B-IN-17 can be used in Parkinson’s disease research[1].
MAO-B-IN-17 (Compound 4j) (10 μM, 24 h) shows no cytotoxic effect on human neuroblastoma cells[1].
| Catalog Number | I042831 |
| CAS Number | 2890188-81-3 |
| Synonyms | 2-(3,5-difluorophenyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline |
| Molecular Formula | C17H17F2NO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H17F2NO2/c1-21-16-5-11-3-4-20(10-12(11)6-17(16)22-2)15-8-13(18)7-14(19)9-15/h5-9H,3-4,10H2,1-2H3 |
| InChIKey | XZTKRGSHRFWZIG-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2CN(CCC2=C1)C3=CC(=CC(=C3)F)F)OC |
| Reference | [1]. Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Med. Chem. Lett. 2022. |
