MAO-B-IN-2

• CAT Number: I045334
• CAS Number: 1253978-24-3
• Molecular Formula: C18H11ClO3
• Molecular Weight: 310.73
• Purity: ≥95%
• Synonyms: 3-[(E)-3-(2-chlorophenyl)prop-2-enoyl]chromen-2-one
• InChI: InChI=1S/C18H11ClO3/c19-15-7-3-1-5-12(15)9-10-16(20)14-11-13-6-2-4-8-17(13)22-18(14)21/h1-11H/b10-9+
• InChIKey: TVTIXYCYMBPAFW-MDZDMXLPSA-N
• SMILES: C1=CC=C2C(=C1)C=C(C(=O)O2)C(=O)C=CC3=CC=CC=C3Cl

MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively.

Reference

[1]. Rehuman NA, et al. Halogenated Coumarin-Chalcones as Multifunctional Monoamine Oxidase-B and Butyrylcholinesterase Inhibitors. ACS Omega. 2021 Oct 12;6(42):28182-28193.
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