For research use only. Not for therapeutic Use.
MAO-B-IN-8 is a potent reversible MAO-B inhibitor and an inhibitor of microglial production of neuroinflammatory mediator. MAO-B-IN-8 can be used for neurodegenerative disease research[1].
| Catalog Number | I043825 |
| CAS Number | 1638956-60-1 |
| Synonyms | (2Z)-6-hydroxy-2-[(2,3,4-trimethoxyphenyl)methylidene]-1-benzofuran-3-one |
| Molecular Formula | C18H16O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H16O6/c1-21-13-7-4-10(17(22-2)18(13)23-3)8-15-16(20)12-6-5-11(19)9-14(12)24-15/h4-9,19H,1-3H3/b15-8- |
| InChIKey | JGOPTESGPYJSBC-NVNXTCNLSA-N |
| SMILES | COC1=C(C(=C(C=C1)C=C2C(=O)C3=C(O2)C=C(C=C3)O)OC)OC |
| Reference | [1]. Ahmed H E Hassan, et al. Positional scanning of natural product hispidol’s ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases. J Enzyme Inhib Me |
