Maprotiline-d3 hydrochloride

• CAT Number: S000486
• CAS Number: 1329496-63-0
• Molecular Formula: C20H21D3ClN
• Molecular Weight: 316.88
• Purity: ≥95%
• IUPAC Name: 3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)-N-(trideuteriomethyl)propan-1-amine;hydrochloride
• InChI: InChI=1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H/i1D3
• InChIKey: NZDMFGKECODQRY-NIIDSAIPSA-N
• SMILES: CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24.Cl

Maprotiline-d3 hydrochloride（Cat No.:S000486） is a deuterated form of maprotiline hydrochloride, where three hydrogen atoms are replaced with deuterium. Maprotiline is a tetracyclic antidepressant used primarily to treat depression, particularly when symptoms include anxiety and insomnia. It works by inhibiting the reuptake of norepinephrine, effectively increasing its levels in the brain. The substitution with deuterium atoms in maprotiline-d3 enhances the drug’s metabolic stability, providing a valuable tool for detailed pharmacokinetic studies.