Maslinic acid

• CAT Number: I003551
• CAS Number: 4373-41-5
• Molecular Formula: C30H48O4
• Molecular Weight: 472.7
• Purity: ≥95%
• Synonyms: 2α,3β-dihydroxy-olean-12-en-28-oic acid
• Target: TNF-α
• Solubility: DMSO: ≥ 28 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
• InChI: InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21-,22+,23-,27-,28+,29+,30-/m0/s1
• InChIKey: MDZKJHQSJHYOHJ-UKSPDLIDSA-N
• SMILES: CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1)C)C(=O)O)C

Maslinic acid (Cat.No:I003551) is a natural triterpene compound found in various plants, including olive trees. It possesses a wide range of biological activities, including anti-inflammatory, antioxidant, anticancer, and hepatoprotective properties. Maslinic acid has shown potential in the treatment of various diseases and is being investigated for its therapeutic applications in both traditional medicine and modern pharmacology.

Reference

[1]. Chang T, et al. Maslinic acid activates mitochondria-dependent apoptotic pathway in cardiac carcinoma. Clin Invest Med. 2014 Aug 1;37(4):E217-24.
[2]. Liu J, et al. Maslinic acid modulates glycogen metabolism by enhancing the insulin signaling pathway and inhibiting glycogen phosphorylase. Chin J Nat Med. 2014 Apr;12(4):259-65.
[3]. Zhang S, et al. Maslinic acid induced apoptosis in bladder cancer cells through activating p38 MAPK signaling pathway. Mol Cell Biochem. 2014 Jul;392(1-2):281-7.
[4]. Yu Y, et al. Maslinic acid potentiates the antitumor activities of gemcitabine in vitro and in vivo by inhibiting NF-κB-mediated survival signaling pathways in human gallbladder cancer cells. Oncol Rep. 2015 Apr;33(4):1683-90.