Mastoparan X

• CAT Number: I042551
• CAS Number: 72093-22-2
• Molecular Formula: C73H126N20O15S
• Molecular Weight: 1555.97
• Purity: ≥95%

Mastoparan X is a GTP-binding regulatory protein (G protein)-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells[1].
Mastoparan X (1.5 mM) interacts with phospholipid bicelles, and results the line broadening[2].
Mastoparan X binds to the membrane, and increases the cell’s permeability to cations leading to a disruption in the electrolyte balance and cell lysis[2].

Reference

[1]. Wakamatsu K, et al. Membrane-bound conformation of mastoparan-X, a G-protein-activating peptide. Biochemistry. 1992 Jun 23;31(24):5654-60.
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[2]. Whiles JA, et al. Orientation and effects of mastoparan X on phospholipid bicelles. Biophys J. 2001 Jan;80(1):280-93.
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