MAT2A inhibitor 2

• CAT Number: I019761
• CAS Number: 13299-99-5
• Molecular Formula: C₁₈H₂₄ClN₃O₃
• Molecular Weight: 365.85
• Purity: ≥95%
• IUPAC Name: 6-(3-methoxyphenyl)-4-methyl-2-(2-morpholin-4-ylethyl)pyridazin-3-one;hydrochloride
• InChI: InChI=1S/C18H23N3O3.ClH/c1-14-12-17(15-4-3-5-16(13-15)23-2)19-21(18(14)22)7-6-20-8-10-24-11-9-20;/h3-5,12-13H,6-11H2,1-2H3;1H
• InChIKey: REOUTEBTFSILJY-UHFFFAOYSA-N
• SMILES: CC1=CC(=NN(C1=O)CCN2CCOCC2)C3=CC(=CC=C3)OC.Cl

MAT2A Inhibitor 2（Cat No.:I019761）is a selective compound targeting methionine adenosyltransferase 2A (MAT2A), an enzyme responsible for producing S-adenosylmethionine (SAM), a key methyl donor in cellular processes. By inhibiting MAT2A, this compound reduces SAM levels, impacting methylation-dependent pathways crucial for cell proliferation and survival. It has shown promise in cancer research, particularly in cancers with methylthioadenosine phosphorylase (MTAP) deletions, as these cancers rely heavily on MAT2A for survival. MAT2A Inhibitor 2 is a valuable tool for studying methylation regulation, offering potential for targeted cancer therapies.