For research use only. Not for therapeutic Use.
MC-1-F2 is the first inhibitor of forkhead Box Protein C2 (FOXC2).
| Catalog Number | I031641 |
| CAS Number | 2376894-10-7 |
| Synonyms | MC1F2; MC 1 F2; MC-1-F2; MC1-F2; MC-1F2 |
| Molecular Formula | C37H46N16O2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 1-(4-((4-(4-(4-amino-6-((4-morpholinophenyl)amino)-1,3,5-triazin-2-yl)piperazin-1-yl)-6-((4-phenoxyphenyl)amino)-1,3,5-triazin-2-yl)amino)butyl)guanidine |
| InChI | InChI=1S/C37H46N16O2/c38-31(39)41-16-4-5-17-42-33-47-35(44-27-10-14-30(15-11-27)55-29-6-2-1-3-7-29)50-37(48-33)53-20-18-52(19-21-53)36-46-32(40)45-34(49-36)43-26-8-12-28(13-9-26)51-22-24-54-25-23-51/h1-3,6-15H,4-5,16-25H2,(H4,38,39,41)(H3,40,43,45,46,49)(H2,42,44,47,48,50) |
| InChIKey | COSUURDQUHTOIY-UHFFFAOYSA-N |
| SMILES | NC(NCCCCNC1=NC(N2CCN(C3=NC(N)=NC(NC4=CC=C(N5CCOCC5)C=C4)=N3)CC2)=NC(NC6=CC=C(OC7=CC=CC=C7)C=C6)=N1)=N |
| Reference | 1: Castaneda M, Chen L, Pradhan L, Li S, Zein R, Lee Y, Lim HS, Nam HJ, Lee J. A Forkhead Box Protein C2 Inhibitor: Targeting Epithelial-Mesenchymal Transition and Cancer Metastasis. Chembiochem. 2018 Jul 4;19(13):1359-1364. doi: 10.1002/cbic.201800022. Epub 2018 May 30. PubMed PMID: 29577543. |
