MC-GGFG-DX8951

• CAT Number: I018173
• CAS Number: 1600418-29-8
• Molecular Formula: C₄₉H₅₁FN₈O₁₁
• Molecular Weight: 946.97
• Purity: ≥95%
• Target: Cell Cycle/DNA Damage

MC-GGFG-DX8951 (Cat.No:I018173) is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.

Reference

[1]. Nakada T, et al. Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1542-1545.