For research use only. Not for therapeutic Use.
MC-PEG2-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
| Catalog Number | I042297 |
| CAS Number | 640267-62-5 |
| Synonyms | N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-6-(2,5-dioxopyrrol-1-yl)hexanamide |
| Molecular Formula | C16H27N3O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H27N3O5/c17-7-10-23-12-13-24-11-8-18-14(20)4-2-1-3-9-19-15(21)5-6-16(19)22/h5-6H,1-4,7-13,17H2,(H,18,20) |
| InChIKey | BRPNMDKROWMZAK-UHFFFAOYSA-N |
| SMILES | C1=CC(=O)N(C1=O)CCCCCC(=O)NCCOCCOCCN |
| Reference | [1]. Hans-Georg Lerchen, et al. Prodrugs of cytotoxic active agents having enzymatically cleavable groups. US20190077752A1. |
