For research use only. Not for therapeutic Use.
Mc-Val-Ala-PAB (Cat No.: I014457) is a versatile cleavable ADC linker ideal for the synthesis of antibody-drug conjugates (ADCs). This linker plays a crucial role in connecting antibodies to potent cytotoxic drugs, enhancing the targeted delivery of therapies in cancer treatment. If you require additional information or have specific inquiries regarding Mc-Val-Ala-PAB, please do not hesitate to reach out to us.
Catalog Number | I014457 |
CAS Number | 1870916-87-2 |
Synonyms | Mc-Val-Ala-PAB, Mc-Val-Ala-PAB-OH; ACD linker.;6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide |
Molecular Formula | C25H34N4O6 |
Purity | ≥95% |
Target | ADC Linker |
Solubility | Soluble in DMSO |
Storage | 2-8°C |
IUPAC Name | 6-(2,5-dioxopyrrol-1-yl)-N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]hexanamide |
InChI | InChI=1S/C25H34N4O6/c1-16(2)23(28-20(31)7-5-4-6-14-29-21(32)12-13-22(29)33)25(35)26-17(3)24(34)27-19-10-8-18(15-30)9-11-19/h8-13,16-17,23,30H,4-7,14-15H2,1-3H3,(H,26,35)(H,27,34)(H,28,31)/t17-,23-/m0/s1 |
InChIKey | DAMSURYLURICHN-SBUREZEXSA-N |
SMILES | CC(C)C(C(=O)NC(C)C(=O)NC1=CC=C(C=C1)CO)NC(=O)CCCCCN2C(=O)C=CC2=O |