MC-Val-Cit-PAB-MMAF

• CAT Number: I017897
• CAS Number: 863971-17-9
• Molecular Formula: C₆₈H₁₀₃N₁₁O₁₆
• Molecular Weight: 1330.61
• Purity: ≥95%
• Target: Drug-Linker Conjugates for ADC

MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.

Reference

[1]. Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.