MCB-613

• CAT Number: I000588
• CAS Number: 1162656-22-5
• Molecular Formula: C19H19N3O
• Molecular Weight: 305.37
• Purity: ≥95%
• Synonyms: (3E,5E)-1-ethyl-3,5-bis(pyridin-3-ylmethylene)piperidin-4-one
• Target: NF-κB
• Solubility: DMSO: ≤ 10 mg/mL
• Storage: Store at -20°C
• InChI: InChI=1S/C19H19N3O/c1-2-22-13-17(9-15-5-3-7-20-11-15)19(23)18(14-22)10-16-6-4-8-21-12-16/h3-12H,2,13-14H2,1H3/b17-9+,18-10+
• InChIKey: LPGYWNGKCLRDNO-BEQMOXJMSA-N
• SMILES: O=C(/C(CN(CC)C/1)=C/C2=CC=CN=C2)C1=CC3=CN=CC=C3

MCB-613 (Cat No.: I000588) is a small molecule compound being studied for its potential therapeutic applications in cancer treatment. It functions as an inhibitor of specific molecular targets involved in cancer cell survival and proliferation, particularly in tumor microenvironments. By blocking these pathways, MCB-613 may disrupt cancer cell growth and metastasis. Preclinical research suggests that MCB-613 may enhance the effectiveness of other cancer therapies, making it a promising candidate for combination treatments. Clinical studies are underway to assess its safety, efficacy, and potential in oncology.

Reference

[1]. Wang L, et al. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10;28(2):240-52.