For research use only. Not for therapeutic Use.
MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues[1][2].
| Catalog Number | I045395 |
| CAS Number | 1100692-14-5 |
| Molecular Formula | C47H64ClN5O13S |
| Purity | ≥95% |
| Reference | [1]. Manu Lopus, et al. Antibody-DM1 conjugates as cancer therapeutics. Cancer Lett. 2011 Aug 28;307(2):113-8. [2]. Liu Y, et al. LC-MS/MS method for the simultaneous determination of Lys-MCC-DM1, MCC-DM1 and DM1 as potential intracellular catabolites of the antibody-drug conjugate trastuzumab emtansine (T-DM1). J Pharm Biomed Anal. 2017 Apr 15;137:170-177. |
