MCL-1/BCL-2-IN-2

• CAT Number: I017579
• CAS Number: 2163793-44-8
• Molecular Formula: C₂₀H₁₅BrN₂O₂S
• Molecular Weight: 427.31
• Purity: ≥95%
• Target: Bcl-2 Family

MCL-1/BCL-2-IN-2 (Cat.No:I017579) is a small molecule inhibitor that targets both MCL-1 and BCL-2 proteins, which play key roles in regulating cell survival and apoptosis. By inhibiting these proteins, MCL-1/BCL-2-IN-2 promotes programmed cell death in cancer cells and shows potential as an anti-cancer therapeutic. Further studies are ongoing to explore its efficacy and safety in preclinical and clinical settings.

Reference

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.