MCL-1/BCL-2-IN-3

• CAT Number: I017578
• CAS Number: 2163793-55-1
• Molecular Formula: C₂₇H₂₅BrN₂O₅S
• Molecular Weight: 569.47
• Purity: ≥95%
• Target: Bcl-2 Family

MCL-1/BCL-2-IN-3 (Cat.No:I017578) is a small molecule inhibitor that targets both MCL-1 and BCL-2 proteins, which play crucial roles in regulating cell survival and apoptosis. By inhibiting these proteins, MCL-1/BCL-2-IN-3 promotes apoptosis and shows potential as an anticancer agent. Further research is ongoing to explore its therapeutic applications and efficacy in various cancer types.

Reference

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.