For research use only. Not for therapeutic Use.
MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
The non-specific luminescence remains almost constant for 10 min after the addition of MCLA hydrochloride (MCLA) and is not significantly influenced by SOD. The MCLA hydrochloride method is, however, 4.5-times more sensitive than the CLA method[1].
| Catalog Number | M116472 |
| CAS Number | 128322-44-1 |
| Synonyms | 6-(4-methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3-ol;hydrochloride |
| Molecular Formula | C14H14ClN3O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C14H13N3O2.ClH/c1-9-14(18)17-8-12(15-7-13(17)16-9)10-3-5-11(19-2)6-4-10;/h3-8,18H,1-2H3;1H |
| InChIKey | MXZACTZQSGYANA-UHFFFAOYSA-N |
| SMILES | CC1=C(N2C=C(N=CC2=N1)C3=CC=C(C=C3)OC)O.Cl |
| Reference | [1]. Kimura H, et al. Highly sensitive and reliable chemiluminescence method for the assay of superoxide dismutase inhuman erythrocytes. FEBS Lett. 1988 Nov 7;239(2):347-50. |
