For research use only. Not for therapeutic Use.
MDK-4111(Cat No.:I011951) is a chemical compound that acts as an agonist of the G-protein-coupled receptor 120 (GPR120). GPR120 is a receptor protein that is involved in various physiological processes, including glucose and lipid metabolism, inflammation, and insulin secretion. MDK-4111 has been shown to have potential as a therapeutic agent in preclinical studies, particularly in the treatment of metabolic disorders such as obesity and type 2 diabetes. Further studies are ongoing to determine its safety and efficacy in humans. However, it is important to note that MDK-4111 is intended for research purposes only and should not be used for any other purposes.
| Catalog Number | I011951 |
| CAS Number | 1234844-11-1 |
| Synonyms | MDK-4111; MDK 4111; MDK4111.;4-[(5-Chloro-2,3-dihydro-2,2-dimethyl-7-benzofuranyl)methoxy]-2,3-dimethylbenzenepropanoic acid |
| Molecular Formula | C22H25ClO4 |
| Purity | ≥95% |
| Target | Free Fatty Acid Receptor |
| Solubility | Soluble in DMSO |
| Storage | Store at 0-8 °C |
| IUPAC Name | 3-[4-[(5-chloro-2,2-dimethyl-3H-1-benzofuran-7-yl)methoxy]-2,3-dimethylphenyl]propanoic acid |
| InChI | InChI=1S/C22H25ClO4/c1-13-14(2)19(7-5-15(13)6-8-20(24)25)26-12-17-10-18(23)9-16-11-22(3,4)27-21(16)17/h5,7,9-10H,6,8,11-12H2,1-4H3,(H,24,25) |
| InChIKey | KOHMUAMPZUHGNV-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1C)OCC2=CC(=CC3=C2OC(C3)(C)C)Cl)CCC(=O)O |
| Reference | </br>1. Preparation of benzofuran derivatives as GPR120 receptor agonists</br> By Shi, Dong Fang; Song, Jiangao; Ma, Jingyuan; Novack, Aaron; Pham, Phuongly; Nashashibi, Imad Fayek; Rabbat, Christopher J.; Chen, Xin</br> From U.S. Pat. Appl. Publ. (2011), US 20110313003 A1 20111222. | Language: English, Database: CAPLUS</br>2. Preparation of benzofuran derivatives as GPR120 receptor agonists</br> By Shi, Dong Fang; Song, Jiangao; Ma, Jingyuan; Novack, Aaron; Pham, Phuongly; Nashashibi, Imad; Rabbat, Christopher J.; Chen, Xin</br> From PCT Int. Appl. (2011), WO 2011159297 A1 20111222. | Language: English, Database: CAPLUS</br>3. Preparation of benzofuranyl substituted phenylalkylcarboxylic acids as Gpr120 receptor agonists</br> By Shi, Dong Fang; Song, Jiangao; Ma, Jingyuan; Novack, Aaron; Pham, Phuongly; Nashashibi, Imad; Rabbat, Christopher J.; Chen, Xin</br> From PCT Int. Appl. (2010), WO 2010080537 A1 20100715. | Language: English, Database: CAPLUS</br> |
