For research use only. Not for therapeutic Use.
Selective 5-HT2A antagonist; rac-M 100907, its more active enantiomer is (+)-MDL 100907 (Axon 1104); Reference standard for [11C]MDL100907 in PET/SPECT study
| Catalog Number | M116068 |
| CAS Number | 139290-69-0 |
| Molecular Formula | C22H28FNO3 |
| Purity | ≥95% |
| IUPAC Name | (2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol |
| InChI | InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3 |
| SMILES | COC1=CC=CC(=C1OC)C(C2CCN(CC2)CCC3=CC=C(C=C3)F)O |
| Reference | HO Kalkman et al. Cataleptogenic effect of subtype selective 5-HT receptor antagonists in the rat. Eur. J. Pharmacol. 1998, 343(2-3), 201-7.
J H Kehne et al. Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats.Neuropsychopharmacol. 1996, 15, 116-124.
C Sanchez et al. In-vivo assessment of 5-HT2A and 5-HT2C antagonistic properties of newer antipsychotics. Behav. Pharmacol. 2000, 11, 291-98. |
