MDL-646

• CAT Number: I031806
• CAS Number: 76822-56-5
• Molecular Formula: C23H40O6
• Molecular Weight: 412.57
• Purity: 98%
• Synonyms: (16R)-Mexiprostil; MDL 646; MDL646; MDL-646
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: methyl 7-[(1R,2R,3R)-2-[(E,3R,4R)-3,4-dihydroxy-4-methoxyoct-1-enyl]-3-hydroxy-5-oxocyclopentyl]heptanoate
• InChI: InChI=1S/C22H38O7/c1-4-5-14-22(27,29-3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)28-2/h12-13,16-17,19-20,24-25,27H,4-11,14-15H2,1-3H3/b13-12+/t16-,17-,19-,20-,22-/m1/s1
• InChIKey: LUZXSWCNVAYLKY-OVRPBERLSA-N
• SMILES: CCCC[C@@]([C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)OC)O)O)(O)OC

MDL-646(CAT: I031806) is a synthetic analog of prostaglandin E1 (PGE1) with gastroprotective properties. It functions by enhancing mucosal defense mechanisms, increasing gastric mucus secretion, and improving blood flow to the gastrointestinal lining, thereby preventing or reducing damage caused by irritants such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acidic conditions. MDL-646 is widely used in gastrointestinal research to study the role of prostaglandins in mucosal protection and to develop therapeutic strategies for conditions like peptic ulcers and gastritis. Its efficacy highlights its significance in advancing gastroenterology and pharmacological research.