For research use only. Not for therapeutic Use.
Mebendazole(Cat No.:A000053)is a broad-spectrum anthelmintic medication widely used to treat parasitic worm infections, including those caused by roundworms, whipworms, hookworms, and tapeworms. It works by inhibiting microtubule formation in the parasite’s cells, disrupting glucose uptake and leading to energy depletion and death. Mebendazole is effective in single or multiple-dose regimens and is well-tolerated with minimal side effects. Its broad efficacy and safety profile make it a key tool in managing helminth infections, improving public health, and supporting deworming programs in endemic regions.
Catalog Number | A000053 |
CAS Number | 31431-39-7 |
Synonyms | Vermox, Telmin, Pantelmin, Mebenvet |
Molecular Formula | C16H13N3O3 |
Purity | ≥95% |
Target | Microtubule/Tubulin |
Solubility | Soluble in DMSO |
Storage | Store at -20°C |
IUPAC Name | methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate |
InChI | InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21) |
InChIKey | OPXLLQIJSORQAM-UHFFFAOYSA-N |
SMILES | COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CC=C3 |
Reference | 1: Silber SA, Diro E, Workneh N, Mekonnen Z, Levecke B, Steinmann P, Umulisa I, 2: Yang CA, Liang C, Lin CL, Hsiao CT, Peng CT, Lin HC, Chang JG. Impact of <br> <br> 5: Mrus J, Baeten B, Engelen M, Silber SA. Efficacy of single-dose 500 mg 6: Celestino Pinto L, de Fátima Aquino Moreira-Nunes C, Soares BM, Burbano RMR, 7: Blom K, Senkowski W, Jarvius M, Berglund M, Rubin J, Lenhammar L, Parrow V, 8: Xiao X, Zhao Y, Zhou Y, Wang Z. Plasma pharmacokinetics and muscle residue 9: Joffe LS, Schneider R, Lopes W, Azevedo R, Staats CC, Kmetzsch L, Schrank A, 10: De Witt M, Gamble A, Hanson D, Markowitz D, Powell C, Al Dimassi S, Atlas M, |