Meclocycline Sulfosalicylate Salt

• CAT Number: R042347
• CAS Number: 73816-42-9
• Molecular Formula: C29H27ClN2O14S
• Molecular Weight: 695.10
• Purity: ≥95%
• Synonyms: 2-Hydroxy-5-sulfo-benzoic Acid (4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide; Meclan; Meclan Cream; Mecloderm; Meclosorb; Meclutin; Traumatoc
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: (4S,4aR,5S,5aR,12aR)-7-chloro-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methylidene-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;2-hydroxy-5-sulfobenzoic acid
• InChI: InChI=1S/C22H21ClN2O8.C7H6O6S/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30;8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h4-5,10,14-15,17,26-28,31,33H,1H2,2-3H3,(H2,24,32);1-3,8H,(H,9,10)(H,11,12,13)/t10-,14-,15+,17+,22+;/m1./s1
• InChIKey: WVJKUGVVYXCLFV-CCHMMTNSSA-N
• SMILES: CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O.C1=CC(=C(C=C1S(=O)(=O)O)C(=O)O)O

Meclocycline Sulfosalicylate Salt（Cat No.:R042347）is a high-purity tetracycline derivative used primarily in pharmaceutical and biochemical research. This compound, a salt form of Meclocycline, combines with sulfosalicylic acid to enhance its solubility and stability, making it ideal for studies in antimicrobial resistance, protein synthesis inhibition, and bacterial infections. It acts by binding to the bacterial ribosome, preventing protein elongation. With its reliable efficacy and chemical stability, Meclocycline Sulfosalicylate Salt is a key reagent for drug development, bacterial studies, and antimicrobial mechanism investigations. It supports high-precision experiments in diverse research areas.

Reference

6-Methylenetetracyclines. I A new class of tetracycline antibiotics. Blackwood R.K. et al. J. Am. Chem. Soc. 1961, 83, 2773. 6-Methylenetetracyclines. III. Preparation and Properties. Blackwood R.K. et al. J. Am. Chem. Soc. 1963, 85, 3943. Meclocycline sulfosalicylate. Topical antibiotic agent for the treatment of acne vulgaris. Knutson D. D. Cutis. 1981, 27, 203.