Meclofenamate Sodium

• CAT Number: A000129
• CAS Number: 6385-02-0
• Molecular Formula: C14H10Cl2NNaO2
• Molecular Weight: 318.1
• Purity: ≥95%
• Synonyms: MECLOFENAMATE SODIUM; Meclomen; Sodium meclofenamate; Meclonax; Movens; Meclofenamic acid sodium
• Target: Metabolic Enzyme/Protease
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at -20°C
• InChI: 1S/C14H11Cl2NO2.Na/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;/h2-7,17H,1H3,(H,18,19);/q;+1/p-1
• InChIKey: OGPIIGMUPMPMNT-UHFFFAOYSA-M
• SMILES: CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)[O-])Cl.[Na+]

Meclofenamate sodium (Cat No.:A000129) is a dual COX-1/COX-2 inhibitor with IC50s of 40 nM and 50 nM, respectively, for the treatment of joint and muscle pain, arthritis, and dysmenorrhea.Meclofenamate sodium is also a non-selective gap junction blocker and a highly selective inhibitor of adiposity and obesity-related ( FTO) enzyme inhibitor.

Reference

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