Medetomidine

• CAT Number: I005178
• CAS Number: 86347-14-0
• Molecular Formula: C13H16N2
• Molecular Weight: 200.28
• Purity: ≥95%
• Synonyms: 5-(1-(2,3-dimethylphenyl)ethyl)-1H-imidazole
• Target: Adrenergic Receptor
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
• InChI: InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)
• InChIKey: CUHVIMMYOGQXCV-UHFFFAOYSA-N
• SMILES: CC1=C(C)C(C(C2=CN=CN2)C)=CC=C1

Medetomidine (CAT: I005178) is a potent and highly selective alpha-2 adrenergic agonist. It acts as a sedative, analgesic, and muscle relaxant. Medetomidine primarily targets the alpha-2 adrenergic receptors in the central nervous system, leading to sedation and analgesia. It is commonly used in veterinary medicine for the sedation and immobilization of animals during procedures and surgeries. Medetomidine’s sedative properties make it useful in reducing stress and anxiety in animals, facilitating handling, and reducing the need for anesthesia. Additionally, it has been investigated for its potential use in human medicine, particularly in the management of pain and anxiety.

Reference

1: Vähä-Vahe T. The clinical efficacy of medetomidine. Acta Vet Scand Suppl. 1989;85:151-3. Review. PubMed PMID: 2571266.
2: Scheinin H, Kallio A, Koulu M, Scheinin M. Pharmacological effects of medetomidine in humans. Acta Vet Scand Suppl. 1989;85:145-7. PubMed PMID: 2571265.
3: Scheinin H, Virtanen R, MacDonald E, Lammintausta R, Scheinin M. Medetomidine–a novel alpha 2-adrenoceptor agonist: a review of its pharmacodynamic effects. Prog Neuropsychopharmacol Biol Psychiatry. 1989;13(5):635-51. Review. PubMed PMID: 2571177.