MELK-8a Dihydrochloride

• CAT Number: I047346
• CAS Number: 1922153-17-0
• Molecular Formula: C25H34Cl2N6O
• Molecular Weight: 505.48
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CN1CCN(CC1)C2=CC=C(C=C2)N3C=C(C=N3)C4=C(C=NC=C4)OCC5CCNCC5

MELK-8a Dihydrochloride is a novel inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 of 2 nM.

Reference

[1] B Barry Touré, et al.J Med Chem. 2016 May 26;59(10):4711-23.