For research use only. Not for therapeutic Use.
Melperone, a butyrophenone, is an antipsychotic agent used for sleep induction which is frequently prescribed in psychiatric setting[1]. Melperone has been used for a variety of indications, including the treatment of schizophrenia, but also for agitation in the elderly[2].
| Catalog Number | I018588 |
| CAS Number | 3575-80-2 |
| Synonyms | 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one |
| Molecular Formula | C16H22FNO |
| Purity | ≥95% |
| InChI | InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 |
| InChIKey | DKMFBWQBDIGMHM-UHFFFAOYSA-N |
| SMILES | CC1CCN(CC1)CCCC(=O)C2=CC=C(C=C2)F |
| Reference | [1]. Hefner G, et al. Melperone but not bisoprolol or metoprolol is a clinically relevant inhibitor of CYP2D6: evidence from a therapeutic drug monitoring survey. J Neural Transm (Vienna). 2015 Nov;122(11):1609-17. [2]. Bobo WV, et al. Melperone, an aytpical antipsychotic drug with clozapine-like effect on plasma prolactin: contrast with typical neuroleptics. Hum Psychopharmacol. 2009 Jul;24(5):415-22. |
