Melphalan Dimer Hydrochloride

• CAT Number: C000380
• CAS Number: 2238824-44-5
• Molecular Formula: C₂₆H₃₅Cl₃N₄O₄ • (HCl) ₓ
• Purity: ≥95%
• Synonyms: 4-[[2-[[4-[Bis(2-chloroethyl)amino]-L-phenylalanyl]oxy]ethyl](2-chloroethyl)amino]-L-phenylalanine Hydrochloride
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Hygroscopic

Melphalan Dimer Hydrochloride(CAT: C000380) holds significance in the field of pharmaceutical chemistry, particularly in the context of antineoplastic drugs. It is recognized as an impurity that arises during the synthesis of Melphalan, which is used as an antineoplastic agent in the treatment of various types of cancer. Identifying and understanding impurities like Melphalan Dimer is crucial for ensuring the quality, safety, and efficacy of the final drug product.

Reference

Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980);