MeOSuc-AAPV-AMC

• CAT Number: R064928
• CAS Number: 72252-90-5
• Molecular Formula: C31H41N5O9
• Molecular Weight: 627.69
• Purity: ≥95%
• Synonyms: methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]-(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate
• IUPAC Name: methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-3-methyl-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate
• InChI: InChI=1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)/t18-,19-,22-,27-/m0/s1
• InChIKey: CMEUDEVBFFPSEI-NFHWZJRKSA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]3CCCN3C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCC(=O)OC

MeOSuc-AAPV-AMC（Cat No.:R064928）is a peptide substrate used in enzymatic assays to measure the activity of specific proteases, particularly those from the caspase family. The compound consists of a methoxy group (MeO) attached to a succinyl group (Suc), followed by the peptide sequence AAPV, which is cleaved by the target enzyme, and a 7-amino-4-methylcoumarin (AMC) fluorophore. Upon cleavage by the protease, AMC is released, producing a fluorescent signal that can be quantitatively measured. MeOSuc-AAPV-AMC is commonly used in research for studying enzyme kinetics and screening for protease inhibitors in drug development.