(+)-Mepivacaine

• CAT Number: I025979
• CAS Number: 24358-84-7
• Molecular Formula: C15H22N2O
• Molecular Weight: 246.35
• Purity: ≥95%
• Synonyms: (2S)-N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide
• InChI: InChI=1S/C15H22N2O/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18)/t13-/m0/s1
• InChIKey: INWLQCZOYSRPNW-ZDUSSCGKSA-N
• SMILES: CC1=C(C(=CC=C1)C)NC(=O)[C@@H]2CCCCN2C

(+)-Mepivacaine(CAT: I025979) is a local anesthetic that selectively blocks sodium ion influx through voltage-gated sodium channels, inhibiting the propagation of action potentials in nerve fibers. This leads to a reversible loss of sensation in the targeted area. Compared to other local anesthetics, (+)-Mepivacaine has a lower incidence of vasodilation and is often used in short-duration procedures for both infiltration and nerve block anesthesia. Its pharmacokinetic profile makes it a versatile option for pain management, particularly in Neurological Disease Research, where it aids in the development of more effective pain control strategies.

Reference

[1]. Fairley J W, et al. An intradermal study of the local anaesthetic and vascular effects of the isomers of mepivacaine[J]. British Journal of Anaesthesia, 1981, 53(11): 1211-1216.