For research use only. Not for therapeutic Use.
Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects[1][2].
| Catalog Number | R002852 |
| CAS Number | 5875-49-0 |
| Synonyms | 8-[(2S)-2,3-dihydroxy-3-methylbutyl]-7-methoxychromen-2-one |
| Molecular Formula | C15H18O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H18O5/c1-15(2,18)12(16)8-10-11(19-3)6-4-9-5-7-13(17)20-14(9)10/h4-7,12,16,18H,8H2,1-3H3/t12-/m0/s1 |
| InChIKey | KGGUASRIGLRPAX-LBPRGKRZSA-N |
| SMILES | CC(C)(C(CC1=C(C=CC2=C1OC(=O)C=C2)OC)O)O |
| Reference | [1]. Huang X, et al. Searching the cytochrome p450 enzymes for the metabolism of meranzin hydrate: a prospective antidepressant originating from Chaihu-Shugan-San. PLoS One. 2014 Nov 26;9(11):e113819. [2]. Li L, et al. Chaihu-Shugan-San and absorbed meranzin hydrate induce anti-atherosclerosis and behavioral improvements in high-fat diet ApoE-/- mice via anti-inflammatory and BDNF-TrkB pathway. Biomed Pharmacother. 2019 Jul;115:108893. |
