Mercaptopurine

• CAT Number: A000317
• CAS Number: 50-44-2
• Molecular Formula: C5H4N4S
• Molecular Weight: 152.18
• Purity: ≥95%
• Synonyms: 6-Mercaptopurine; 50-44-2; Purinethol; Mercapurin; 6-Thiopurine
• Target: Autophagy
• Solubility: >7.6mg/mL in DMSO
• Storage: -20°C

Mercaptopurine（Cat No.:A000317）is an antimetabolite drug primarily used in the treatment of acute lymphoblastic leukemia (ALL) and certain autoimmune diseases, such as inflammatory bowel disease. It functions as a purine analog, inhibiting DNA and RNA synthesis by interfering with the metabolism of purines. By disrupting the proliferation of rapidly dividing cells, mercaptopurine induces apoptosis in cancer cells. Its effectiveness is often enhanced when used in combination with other chemotherapy agents. However, it may cause side effects such as myelosuppression, necessitating careful monitoring during treatment. 

Reference

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