Mesaconitine

• CAT Number: I002944
• CAS Number: 2752-64-9
• Molecular Formula: C33H45NO11
• Molecular Weight: 631.71
• Purity: ≥95%
• Target: TNF Receptor
• Solubility: 10 mM in DMSO
• Storage: 2-8°C(protect from light)
• IUPAC Name: [(1S,2R,3R,4R,5R,6S,7S,8R,9R,13R,14R,16S,17S,18R)-8-acetyloxy-5,7,14-trihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate
• InChI: InChI=1S/C33H45NO11/c1-16(35)45-33-21-18(13-31(39,28(43-6)26(33)37)27(21)44-29(38)17-10-8-7-9-11-17)32-20(41-4)12-19(36)30(15-40-3)14-34(2)25(32)22(33)23(42-5)24(30)32/h7-11,18-28,36-37,39H,12-15H2,1-6H3/t18-,19-,20+,21-,22+,23+,24-,25?,26+,27-,28+,30+,31-,32+,33-/m1/s1
• InChIKey: XUHJBXVYNBQQBD-TUWOXVOMSA-N
• SMILES: CC(=O)OC12C3C(CC(C3OC(=O)C4=CC=CC=C4)(C(C1O)OC)O)C56C(CC(C7(C5C(C2C6N(C7)C)OC)COC)O)OC

Mesaconitine（Cat No.:I002944） is an aconite alkaloid found in Aconiti tuber. It exhibits the ability to elevate intracellular calcium levels ([Ca2+]i) in endothelial cells. This effect is achieved through the influx of calcium ions from the extracellular space. Mesaconitine’s action on endothelial cells increases intracellular calcium concentration, potentially impacting various cellular processes and signaling pathways regulated by calcium.