For research use only. Not for therapeutic Use.
Metamfazone（Cat No.:I032003）is an experimental compound that belongs to a class of drugs known as farnesyltransferase inhibitors. Farnesyltransferase is an enzyme that plays a crucial role in the post-translational modification of proteins, particularly in the attachment of farnesyl groups to proteins involved in cell signaling, growth, and cancer progression. By inhibiting this enzyme, Metamfazone aims to block the farnesylation of target proteins, potentially reducing tumor growth and metastasis in cancer cells. Research is ongoing to determine its effectiveness in treating various cancers, including those with mutations in the Ras signaling pathway, which is involved in many malignancies.
| Catalog Number | I032003 |
| CAS Number | 54063-49-9 |
| Synonyms | AGN 20, AGN-20, AGN20, Metamfazone, Metamfazonum, Methamphazone |
| Molecular Formula | C11H11N3O |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-amino-6-methyl-2-phenylpyridazin-3-one |
| InChI | InChI=1S/C11H11N3O/c1-8-7-10(12)11(15)14(13-8)9-5-3-2-4-6-9/h2-7H,12H2,1H3 |
| InChIKey | HARUKDOMEBNBIV-UHFFFAOYSA-N |
| SMILES | CC1=NN(C(=O)C(=C1)N)C2=CC=CC=C2 |
| Reference | No references available at this time. |
