Methenamine borate

• CAT Number: I032061
• CAS Number: 27401-86-1
• Molecular Formula: C6H15BN4O3
• Molecular Weight: 202.02
• Purity: 98%
• Synonyms: Borohexamine; Methenamine borate; Urotropin borate
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1,3,5,7-tetraazaadamantane borate
• InChI: InChI=1S/C6H12N4.BH3O3/c1-7-2-9-4-8(1)5-10(3-7)6-9;2-1(3)4/h1-6H2;2-4H
• InChIKey: MWWHVOZLSBBRDS-UHFFFAOYSA-N
• SMILES: OB(O)O.C1N2CN3CN(CN1C3)C2

Methenamine borate (Cat No.: I032061) is a compound commonly used as a urinary antiseptic. It works by releasing formaldehyde in acidic urine, which helps to prevent or control bacterial infections in the urinary tract. This slow-release mechanism makes it effective for long-term prophylaxis. Methenamine borate is generally well-tolerated, with minimal resistance development, making it suitable for recurrent urinary tract infection (UTI) prevention. It is often used when antibiotics are not ideal or have failed. Proper hydration and acidic urine are necessary for effectiveness.

Reference

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2: Zhang L, Hao W, Xu L, Gao Y, Wang X, Zhu D, Chen Z, Zhang X, Chen H, Mei L. A pH-sensitive methenamine mandelate-loaded nanoparticle induces DNA damage and apoptosis of cancer cells. Acta Biomater. 2017 Oct 15;62:246-256. doi: 10.1016/j.actbio.2017.08.019. Epub 2017 Aug 16. PubMed PMID: 28822844.
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