For research use only. Not for therapeutic Use.
Methiocarb is a carbamate pesticide which is used as a bird repellent, insecticide, acaricide and molluscicide. Methiocarb inhibits reversibly acetylcholinesterase activity resulting in a cholinergic stimulation making methiocarb a potent neurotoxin.
| Catalog Number | R021316 |
| CAS Number | 2032-65-7 |
| Synonyms | Methylcarbamic Acid 4-(Methylthio)-3,5-xylyl Ester; 3,5-Dimethyl-4-(methylthio)phenol Methylcarbamate; 3,5-Dimethyl-4-(methylthio)phenyl Methylcarbamate; 4-(Methylthio)-3,5-xylyl Methylcarbamate; 4-(Methylthio)-3,5-xylyl-N-methylcarbamate; 4-Methylth |
| Molecular Formula | C11H15NO2S |
| Purity | ≥95% |
| Storage | -20°C |
| IUPAC Name | (3,5-dimethyl-4-methylsulfanylphenyl) N-methylcarbamate |
| InChI | InChI=1S/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13) |
| InChIKey | YFBPRJGDJKVWAH-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC(=C1SC)C)OC(=O)NC |
| Reference | </br>1:Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARα activities. Fujino C, Tamura Y, Tange S, Nakajima H, Sanoh S, Watanabe Y, Uramaru N, Kojima H, Yoshinari K, Ohta S, Kitamura S.J Toxicol Sci. 2016;41(5):677-91. doi: 10.2131/jts.41.677. PMID: 27665777 Free Article</br>2:In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities. Tange S, Fujimoto N, Uramaru N, Wong FF, Sugihara K, Ohta S, Kitamura S.Environ Toxicol Pharmacol. 2016 Jan;41:289-97. doi: 10.1016/j.etap.2015.08.014. Epub 2015 Aug 14. PMID: 26774076 </br>3:Degradation of methiocarb by monochloramine in water treatment: kinetics and pathways. Qiang Z, Tian F, Liu W, Liu C.Water Res. 2014 Mar 1;50:237-44. doi: 10.1016/j.watres.2013.12.011. Epub 2013 Dec 18. PMID: 24380738 </br>4:Determination of methiocarb and its degradation products, methiocarb sulfoxide and methiocarb sulfone, in bananas using QuEChERS extraction. Plácido A, Paíga P, Lopes DH, Correia M, Delerue-Matos C.J Agric Food Chem. 2013 Jan 16;61(2):325-31. doi: 10.1021/jf304027s. Epub 2013 Jan 3. PMID: 23252625 </br>5:Methiocarb poisoning of a horse in Australia. Kaye BM, Elliott CR, Jalim SL.Aust Vet J. 2012 Jun;90(6):221-4. doi: 10.1111/j.1751-0813.2012.00910.x. Epub 2012 Apr 9. PMID: 22632285 </br>6:Acute effects of methiocarb on oxidative damage and the protective effects of vitamin E and taurine in the liver and kidney of Wistar rats. Ozden S, Catalgol B, Gezginci-Oktayoglu S, Karatug A, Bolkent S, Alpertunga B.Toxicol Ind Health. 2013 Feb;29(1):60-71. doi: 10.1177/0748233712446719. Epub 2012 May 23. PMID: 22623520 </br>7:A novel spectrofluorometric method for the determination of methiocarb using an amphiphilic p-sulfonatocalix[4]arene. Ding XP, Tang DB, Li T, Wang SF, Zhou YY.Spectrochim Acta A Mol Biomol Spectrosc. 2011 Oct 15;81(1):44-7. doi: 10.1016/j.saa.2011.05.038. Epub 2011 May 23. PMID: 21737343 </br>8:Kinetics and mechanism for methiocarb degradation by chlorine dioxide in aqueous solution. Tian F, Qiang Z, Liu C, Zhang T, Dong B.Chemosphere. 2010 Apr;79(6):646-51. doi: 10.1016/j.chemosphere.2010.02.015. Epub 2010 Mar 1. PMID: 20189628 </br>9:Effects of methiocarb on lipid peroxidation and glutathione level in rat tissues. Ozden S, Alpertunga B.Drug Chem Toxicol. 2010;33(1):50-4. doi: 10.3109/01480540903130708. PMID: 19827908 </br>10:Immunochromatographic colloidal carbon-based assay for detection of methiocarb in surface water. Blazková M, Micková-Holubová B, Rauch P, Fukal L.Biosens Bioelectron. 2009 Dec 15;25(4):753-8. doi: 10.1016/j.bios.2009.08.023. Epub 2009 Aug 22. PMID: 19765968 |
