For research use only. Not for therapeutic Use.
Methocarbamol is a skeletal muscle relaxant. This compound is a carbamate of guaifenesin. Methocarbamol has been observed to bind to carbonic anhydrase I and II with 1000-fold more specificity for carbonic anhydrase I.
| Catalog Number | A001218 |
| CAS Number | 532-03-6 |
| Synonyms | AHR 85 |
| Molecular Formula | C11H15NO5 |
| Purity | ≥95% |
| Target | Sodium Channel |
| Storage | 3 years -20C powder |
| InChI | InChI=1S/C11H15NO5/c1-15-9-4-2-3-5-10(9)16-6-8(13)7-17-11(12)14/h2-5,8,13H,6-7H2,1H3,(H2,12,14) |
| InChIKey | GNXFOGHNGIVQEH-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC=C1OCC(COC(=O)N)O |
| Reference | </br>1:Comparison of atracurium and methocarbamol for preventing succinylcholine-induced muscle fasciculation: A randomized controlled trial. Shabanian G, Shabanian M, Shabanian A, Heidari-Soureshjani S.J Adv Pharm Technol Res. 2017 Apr-Jun;8(2):59-62. doi: 10.4103/japtr.JAPTR_172_16. PMID: 28516057 </br>2:Methocarbamol use is associated with decreased hospital length of stay in trauma patients with closed rib fractures. Patanwala AE, Aljuhani O, Kopp BJ, Erstad BL.Am J Surg. 2017 Jan 6. pii: S0002-9610(17)30021-1. doi: 10.1016/j.amjsurg.2017.01.003. [Epub ahead of print] PMID: 28088301 </br>3:Inhibition of pseudoperoxiadse activity of human red blood cell hemoglobin by methocarbamol. Minai-Tehrani D, Toofani S, Yazdi F, Minai-Tehrani A, Mollasalehi H, Bakhtiari Ziabari K.Int J Biol Macromol. 2017 Jan;94(Pt B):788-792. doi: 10.1016/j.ijbiomac.2016.09.049. Epub 2016 Sep 16. PMID: 27645932 </br>4:[Methocarbamol: central building block in multimodal therapy]. [No authors listed]MMW Fortschr Med. 2016 May 12;158(9):72-3. German. No abstract available. PMID: 27333626 </br>5:Pharmacokinetics of methocarbamol and phenylbutazone in exercised Thoroughbred horses. Knych HK, Stanley SD, Seminoff KN, McKemie DS, Kass PH.J Vet Pharmacol Ther. 2016 Oct;39(5):469-77. doi: 10.1111/jvp.12298. Epub 2016 Feb 29. PMID: 26924025 </br>6:Sinus Tachycardia Induced by Methocarbamol and Repetitive Transcranial Magnetic Stimulation (rTMS). Dobek CE, Dipinto AA, Kuan AJ, Lam RW, Blumberger DM, Downar J, Daskalakis ZJ, Vila-Rodriguez F.Brain Stimul. 2016 Jan-Feb;9(1):156-8. doi: 10.1016/j.brs.2015.10.012. Epub 2015 Nov 24. No abstract available. PMID: 26792632 </br>7:Effect of Methocarbamol on Acute Pain After Traumatic Injury. Aljuhani O, Kopp BJ, Patanwala AE.Am J Ther. 2017 Mar/Apr;24(2):e202-e206. doi: 10.1097/MJT.0000000000000364. PMID: 26469684 </br>8:[Methocarbamol in acute low back pain. A randomized double-blind controlled study]. Emrich OM, Milachowski KA, Strohmeier M.MMW Fortschr Med. 2015 Jul;157 Suppl 5:9-16. doi: 10.1007/s15006-015-3307-x. Epub 2015 Jul 13. German. PMID: 26168743 </br>9:Smart manipulation of ratio spectra for resolving a pharmaceutical mixture of Methocarbamol and Paracetamol. Essam HM, Abd-El Rahman MK.Spectrochim Acta A Mol Biomol Spectrosc. 2015 Apr 15;141:1-9. doi: 10.1016/j.saa.2015.01.017. Epub 2015 Jan 21. PMID: 25659736 </br>10:Extraction of methocarbamol from human plasma with a polypyrrole/multiwalled carbon nanotubes composite decorated with magnetic nanoparticles as an adsorbent followed by electrospray ionization ion mobility spectrometry detection. Saraji M, Khayamian T, Hashemian Z.J Sep Sci. 2014 Dec;37(23):3518-25. doi: 10.1002/jssc.201400614. Epub 2014 Oct 21. PMID: 25243817 |
