For research use only. Not for therapeutic Use.
Methotrexate-d7 Heptaglutamate is a deuterated form of methotrexate heptaglutamate, where seven hydrogen atoms are replaced with deuterium atoms. This compound is specifically designed for advanced research applications, including pharmacokinetic studies, drug metabolism research, and isotope-dilution mass spectrometry. Methotrexate-d7 Heptaglutamate is particularly valuable in investigating the metabolic pathways and cellular uptake of methotrexate, especially its polyglutamated forms, which are crucial for its retention and efficacy in cells. The deuterium labeling allows for precise tracking and quantification in biological systems, making this compound an essential tool in cancer research, particularly in the study of antifolate drugs and their mechanisms of action. Its high purity and isotopic labeling ensure accurate and reproducible results in analytical and clinical research, contributing to the optimization of methotrexate-based therapies.
| Catalog Number | R068145 |
| Molecular Formula | C50H57D7N14O23 |
| Purity | ≥95% |
| Storage | RT |
