Methyl 2,5-dihydroxycinnamate

• CAT Number: R000230
• CAS Number: 63177-57-1
• Molecular Formula: C10H10O4
• Molecular Weight: 194.18
• Purity: ≥95%
• Synonyms: methyl (E)-3-(2,5-dihydroxyphenyl)prop-2-enoate
• InChI: InChI=1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3/b5-2+
• InChIKey: BQCNSTFWSKOWMA-GORDUTHDSA-N
• SMILES: COC(=O)C=CC1=C(C=CC(=C1)O)O

Methyl 2,5-dihydroxycinnamate is an erbstatin analog and a stable, potent inhibitor of EGFR kinase activity[1].

Reference

[1]. Umezawa K, et al. Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors. FEBS Lett. 1990 Jan 29;260(2):198-200.
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