Methyl 3-aMino-2-(aMinoMethyl)propanoate

• CAT Number: M131578
• CAS Number: 159029-33-1
• Molecular Formula: C5H12N2O2
• Molecular Weight: 132.16
• Purity: ≥95%
• Synonyms: Propanoic acid, 3-amino-2-(aminomethyl)-, methyl ester
• Storage: -20°C
• IUPAC Name: methyl 3-amino-2-(aminomethyl)propanoate
• InChI: InChI=1S/C5H12N2O2/c1-9-5(8)4(2-6)3-7/h4H,2-3,6-7H2,1H3
• InChIKey: FECXFRRSZGZESE-UHFFFAOYSA-N
• SMILES: COC(=O)C(CN)CN

Methyl 3-amino-2-(aminomethyl)propanoate（Cat No.:M131578） is a chemical compound with the molecular formula C5H12N2O2. It is a derivative of proline and contains both an amino group and a methyl ester group. This compound is often used as a building block in organic synthesis to introduce the proline moiety into larger molecules. The presence of both an amino group and a methyl ester group makes it a versatile intermediate for the synthesis of various pharmaceuticals and other organic compounds.

Reference

[1]. Katritzky, Alan R., O. Lingibe, and B. Yang.
A convenient one-pot preparation of methyl α-aryl-β-primarylamino alkanoates.
Six examples of α-aryl-β primarylamino esters (V) were synthesized by a convenient one pot methodology, i.e., reaction of lithiated methyl α-aryl-acetates with 1-(triphenylphosphoroylideneaminomethyl)benzotriazole (BETMIP) followed by hydrolysis.
Chemistry of Heterocyclic Compounds 31.8 (1995): 890-892.

[2].Nishida, Hidemitsu, et al.
Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.
Compounds containing an ethylenediamine structure in place of the piperazine ring of M55113 (1) and M55551 (2) were synthesized to investigate the effects of a piperazine moiety and evaluated for activity as factor Xa (FXa) inhibitors. Most such compounds, however, exhibited lower activity (1/10—1/100) than that of M55113 and M55551 as FXa inhibitors
Chemical and pharmaceutical bulletin 52.4 (2004): 459-462.