Methyl 3-hydroxy-4,5-dimethoxybenzoate

• CAT Number: R018804
• CAS Number: 83011-43-2
• Molecular Formula: C10H12O5
• Molecular Weight: 212.20
• Purity: ≥95%
• Target: Bacterial
• Storage: 2-8°C
• IUPAC Name: methyl 3-hydroxy-4,5-dimethoxybenzoate
• InChI: InChI=1S/C10H12O5/c1-13-8-5-6(10(12)15-3)4-7(11)9(8)14-2/h4-5,11H,1-3H3
• InChIKey: LCIFXEQPXQVBGL-UHFFFAOYSA-N
• SMILES: COC1=CC(=CC(=C1OC)O)C(=O)OC

Methyl 3,4-dimethoxy-5-hydroxybenzoate（Cat No.:R018804）is an ester derivative that serves as a crucial intermediate in the synthesis of acotiamide. Acotiamide hydrochloride, developed by Japan Zeria Shinyaku Kogyo Co., Ltd., is a novel M1 and M2 receptor antagonist. It has received approval for the treatment of symptoms such as postprandial fullness, upper abdominal distension, and early satiety caused by functional dyspepsia (FD). The compound acts by enhancing gastric motility and improving gastrointestinal symptoms. Acotiamide hydrochloride represents an important therapeutic option for managing FD-related symptoms.