For research use only. Not for therapeutic Use.
Eicosapentaenoic acid (EPA) is an ω-<wbr></wbr>3 fatty acid which can have beneficial effects on vascular and immune physiology. Also, EPA serves as a precursor for resolvins, mediators that help resolve inflammatory processes. EPA methyl ester is a more lipid-<wbr></wbr>soluble form of EPA. This compound may be more desirable than the free acid in certain formulations. In addition, the methyl ester form of EPA may serve as a prodrug, since it should facilitate uptake of EPA and then be hydrolyzed by esterases to generate the free acid after uptake into cells.
| Catalog Number | R023616 |
| CAS Number | 2734-47-6 |
| Synonyms | (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid Methyl Ester;?(all-Z)-5,8,11,14,17-Eicosapentaenoic Acid Methyl Ester; all-cis- 5,8,11,14,17-Eicosapentaenoic Acid Methyl Ester; Methyl 5Z,8Z,11Z,14Z,17Z-eicosapentaenoate; Methyl all-cis-5,8,11, |
| Molecular Formula | C21H32O2 |
| Purity | ≥95% |
| Target | Disease Research Fields |
| Storage | -20°C |
| IUPAC Name | methyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate |
| InChI | InChI=1S/C21H32O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(22)23-2/h4-5,7-8,10-11,13-14,16-17H,3,6,9,12,15,18-20H2,1-2H3/b5-4-,8-7-,11-10-,14-13-,17-16- |
| InChIKey | QWDCYFDDFPWISL-JEBPEJKESA-N |
| SMILES | CCC=CCC=CCC=CCC=CCC=CCCCC(=O)OC |
| Reference | <br>1. C. Song, S. Zhao, Expert Opin Investig Drugs, Vol. 16(10) pp. 1627-1638, 2007<br>2. Masahiro Murata, Journal of Biological Chemistry, Vol. 276 pp. 31422-31428, 2001<br>3. Jason D. Morrow, Journal of Biological Chemistry, Vol. 283 pp. 12043-12055, 2008</br></br></br> |
