For research use only. Not for therapeutic Use.
Linoleic acid methyl ester is a more lipid-soluble form of linoleic acid (Item No. <span class=/itemid/>90150</span>). Linoleic acid is an essential fatty acid and one of the most abundant PUFAs in the Western diet. Deficiencies in linoleic acid are linked to defective wound healing, growth retardation, and dermatitis. Linoleic acid is metabolized by 15-LO in both plants and animals to form 9(S)- and 13(S)-HODE (Item Nos. <span class=/itemid/>38410</span> and <span class=/itemid/>38610</span>, respectively).
| Catalog Number | R040244 |
| CAS Number | 112-63-0 |
| Synonyms | (9Z,12Z)-9,12-Octadecadienoic Acid Methyl Ester; Linoleic Acid Methyl Ester; (9Z,12Z)-Octadecadienoic Acid Methyl Ester; Methyl (9Z,12Z)-Octadeca-9,12-dienoate; Methyl (9Z,12Z)-Octadecadienoate; Methyl (Z,Z)-9,12-Octadecadienoate; Methyl 9-cis,12-cis |
| Molecular Formula | C19H34O2 |
| Purity | ≥95% |
| Target | Tyrosinase |
| Storage | -20°C |
| IUPAC Name | methyl (9Z,12Z)-octadeca-9,12-dienoate |
| InChI | InChI=1S/C19H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21-2/h7-8,10-11H,3-6,9,12-18H2,1-2H3/b8-7-,11-10- |
| InChIKey | WTTJVINHCBCLGX-NQLNTKRDSA-N |
| SMILES | CCCCCC=CCC=CCCCCCCCC(=O)OC |
| Reference | <br>1. L. Chuang et al. “Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase” Lipids, Vol. 36(10),pp. 1099-1103, 2001<br>2. M. Wadman et al. “Conversion of linoleic acid into novel oxylipins by the mushroom Agaricus bisporus” Lipids, Vol. 40(11) pp. 1163-1170, 2005<br>3. P. Elias, B. Brown, V. Ziboh “The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in BarrierFunction” Journal of Investigative Dermatology, Vol.74 pp. 230–233, 1980</br></br></br> |
