For research use only. Not for therapeutic Use.
Myristic acid methyl ester is an esterified version of the free acid, which is less water soluble but more amenable for the formulation of myristate-containing diets and dietary supplements. Myristic acid (Item No. <span class=/itemid/>13351</span>) is a 14-carbon saturated (14:0) fatty acid. <em>In vivo</em>, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation. In addition, there are examples where N-myristoylation occurs post-translationally, when a hidden myristoylation pattern is exposed.
| Catalog Number | R045714 |
| CAS Number | 124-10-7 |
| Synonyms | Myristic Acid Methyl Ester; Emery 2214; Metholeneat 2495; Methyl Myristate; Methyl n-Tetradecanoate; Methyl Tetradecanoate; NSC 5029; Pastel M 14; Pastell M 14; Uniphat A50 |
| Molecular Formula | C15H30O2 |
| Purity | ≥95% |
| Target | Disease Research Fields |
| Storage | -20°C |
| IUPAC Name | methyl tetradecanoate |
| InChI | InChI=1S/C15H30O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15(16)17-2/h3-14H2,1-2H3 |
| InChIKey | ZAZKJZBWRNNLDS-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCC(=O)OC |
| Reference | <br>1. K. Tomita et al. “Plasma Free Myristic Acid Proportion Is a Predictor of Nonalcoholic Steatohepatitis” Digestive Diseases and Sciences, vol. 56 pp. 3045-3052, 2011<br>2. H. Iijima et al. “The Inhibitory Action of Long-Chain Fatty Acids on the DNA Binding Activity of p53” Lipids, vol. 41 pp. 521-527, 2006<br>3. W. Bernhard et al. “Increased palmitoyl-myristoyl-phosphatidylcholine in neonatal rat surfactant is lung specific and correlates with oral myristic acidsupply” Journal of Applied Physiology, vol. 111 pp. 449-457, 2011<br>4. R. Micha and D. Mozaffarian “Saturated Fat and Cardiometabolic Risk Factors, Coronary Heart Disease, Stroke, and Diabetes: a Fresh Look at theEvidence” Lipids, vol. 45 pp. 893-905, 2010</br></br></br></br> |
